78UUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUUU ¥xÆW¨Å»Äµß¨ó·|

¥xÆW¨Å»Äµß¨ó·|°ò©ó¤½¥­¡B¤½¥¿¤ÎÁקK»~¾É®ø¶OªÌ¥ß³õ¡A¥xÆW¨Å»Äµß¨ó·|¤£´À¥ô¦ó¥«°â¨Å»Äµß¬ÛÃö²£«~¡]§tÀu¹T¨Å¡BÃæ»Ã¨Å¡B¨Å»Äµß¯»¾¯¡B¨Å»Äµß¿õ¾¯¡^°µ±ÀÂË¡B¼s§i¡B¥N¨¥©Î­I®Ñ¡C
    
 

¨Å»Äµß²¤¶
¨Å»Äµßªº¥Í¬¡Àô¹Ò
¨Å»Äµß¹ï­G¸z¹Dªº¯q³B
¨Å»Äµß»P¸z¹DµßÂO
¨Å»Äµß»P¤HÅé§K¬Ì¤O
¨Å»Äµßªº«O°·¥\¯à
¨Å»Äµß¦b¥«­±¤W­¹«~À³¥Î¤§²{ªp
¨Å»Äµß¥¼¨Ó²£«~ªºµo®iÁͶÕ

¨Å»Äµß²¤¶¡G
¡u¨Å»Äµß¡v¬O«ü¯à°÷¥NÁ¿}Ãþ¡B²£¥Í50%¥H¤W¨Å»Ä¤§²Óµß¡A¨ã¦³³o¨Ç¥\¯àªº²Óµß¥]¬A¤F¡G¨Å»Ä±ìµß(Lactobacillus)¡BÁä²yµß(Streptococcus)¡B©À²yµß(Leuconostoc)µ¥¡C¦ý¨Å»Äµß¬°²ßºD¥Î»y¡A¨Ã¤£¬O¤ÀÃþ¾Ç¤W¥¿¦¡¥Î»y¡C§Ú­Ì¸g±`Á¿ªºÂùª[±ìµß©Î¤ñµá¼wµß·|²£¥Í¨Å»Ä¤Î¾L»Ä¡A¦ý¨Å»Ä¤£¨ì50%¡A©Ò¥HÄY®æ»¡¨Ó¤£À³ºÙ¬°¨Å»Äµß¡C¦ý­Y¥Ñ«O°·Àç¾iÆ[ÂI¦Ó¨¥¡AÂùª[±ìµß¦P¼Ë¨ã¦³¦w¥þ¡B°·±dµ¥¨Å»Äµß©Ò¼Ðº]¤§§Î¶H¡A±N¤§¯Ç¤J¨Å»Äµß®a±Ú¥ç¬O²z©Ò·íµM¡C
¤HÃþ¶¼¥ÎÃæ»Ã¨Å«~¾ú¥v«D±`±y¤[¡A©Ò¥H¡A¨Å»Äµß¤@ª½³Q»{¬°¬O«D±`¦w¥þªºµßºØ¡]GRAS,generally reyarded as safe¡^¡A¬O³Ì¨ã¥Nªí©Êªº¸z¤º¦³¯qµß¡C¡]¨ó·|²z¨Æªø / ½²­^³Ç¡^

¨Å»Äµßªº¥Í¬¡Àô¹Ò¡G
¨Å»Äµß¹ïÀç¾i»Ý¨D¯S§OÄY­V¡A°£¤F§@¬°¯à·½¤§¿}Ãþ¥~¡A¨Å»Äµß»Ý­n¦UºØ¦U¼Ëªº®ò°ò»Ä¡Bºû¥Í¯À¡BÄqª«½èµ¥¡A¥Hºû«ù¨ä¥Íªø¡C¨Å»Äµß¬O¤@ºØ­Ý©Ê¶û®ðµß¡A¤ñ¸û³ßÅw¦bµL®ñª¬ºA¤U¥Íªø¡A¦ý¤]¤£·|¦]¬°©M®ñ®ð±µÄ²¦Ó¦º¤`¡C¾ãÅé¦Ó¨¥¡A¦b¦ÛµM¬É¤¤¡A¥u­n¦³°Ê´Óª«¬¡°Êªº¦a¤è¡A´N·|¦³¨¬°÷ªºÀç¾i¨Ñ¨Å»Äµß¥Í¦s¡CÁ|¤Z°Ê´Óª«ªº¤Àªcª«¡]¦p¨Å¥Ä¡B¾ð²Gµ¥¡^¡A©Î¨ä´ÝÀe°ï¿n³B¡A³£¬O¾A¦X¨Å»Äµß¥Í¨|ªº³õ©Ò¡C¤]³\¦b³o¨Ç°ï¿nª«ªí­±¦³¨ä¥L¦n®ð©Ê·L¥Íª«Àu¶Õ¥Íªø¡A¦ý¨ä¤º³¡¯Ê®ñ³¡¤À´N¬O¨Å»Äµßªº¤Ñ¦a¡C§ó¨ãÅ骺»¡¡A¾A¦X¨Å»Äµß¥Íªøªº³õ©Ò©M°Êª«¬ÛÃöªÌ¦³¨Å¥Ä¡B®ø¤Æ¹D¡B³±¹D¡BÁT«Kµ¥¡A©M´Óª«¬ÛÃöªº«h¦³ªá»e¡B¾ð²G¡B´Óª«´ÝÀe¡BªG¹ê·l¶Ë³¡¦ìµ¥¡C¤HÃþ©Ò²£»sªº¦UºØÃæ»Ã­¹«~¡]¦pªwµæ¡BÂæªoµ¥¡^¤¤¡A¤]¦³³\¦h¨Å»Äµßµo´§¿n·¥ªº¥\¯à¡C³o¨Ç¨Å»Äµß¹ï»s«~¤§­·¨ý«~½è¼vÅT¬Æ¤j¡C
¤HÅé®ø¤Æ¹D¤¤¦s¦b³\¦h¨Å»Äµß¡A¨ä¼Æ¥Ø©MºØÃþ·|ÀH¦~ÄÖ¦Ó§ïÅÜ¡A¦p¥®¨à¸z¹D¤¤¡AÂùª[±ìµß¸û¦h¡A¦Ó¦Ñ¦~¤H«h¥H¨Å»Ä±ìµß¸û¦h¡C¡]¨ó·|²z¨Æªø / ½²­^³Ç¡^

¨Å»Äµß¹ï­G¸z¹Dªº¯q³B¡G
¨Å»Äµß¬O¡u¯q¥Íµß¡v¤¤³Ì­«­nªº¤@¸s¡A¯q¥Íµßªº©w¸q¬°¡u¬Y¤@ºØ©Î½Æ¼ÆºØ·L¥Íª«·íÁý­¹¤©¤HÃþ©Î°Êª«®É¥i¼W¶i¨ä¸z¤ºµßÂO¤§«~½è¡v¡C¨Å»Äµß¯à¼W¶i¸z¤ºÂO«~½è¤§§@¥Î¾÷Âà¥i¯à¬O(1)¥Í²£¦³¾÷»Ä¡B­°§C¸zpH¡A(2)©M¦³®`µßÄvª§¾i¥÷¡A(3)ªþµÛ©ó¸zÖß½¤¤W¥Ö¡A´î¤Ö¦³®`µß¼W´Þ³õ©Ò¡A(4)²£¥Í§Üµßª«½èµ¥¡C¨Å»Äµß­nµo´§¾ã¸z®ÄªG¡A·Q·íµMªº¥²¶·­n¯à©wµÛ©ó¸z¹D¡C¥Ø«e¦³³\¦hÃæ»Ã¨Å©Î¾ã¸z¥Î¨Å»Äµß»s¾¯¨Ï¥Î¥Ñ¤H¸z¹D¤¤¤ÀÂ÷¥X¨Óªº¨Å»Äµß¡A¥H¨D´£¤É¨ä¦b¤HÅ餺ªº©wµÛ©Ê¡C³\¦hÁ{§É¹êÅç¤]ÃÒ¹ê³oÃþ¨Å»Äµß½T¹ê¦³¤£¿ùªº¾ã¸z®ÄªG¡A¤]½T¹ê·|­°§C¸z¤º¤£¦nªºµßÃþ¡C
¥Ø«e°ê¤º³\¦hÃæ»Ã¨Å²£«~¡A¬Ò¹ê¬I¤j³W¼Ò¤HÅ鶼¥Î¹êÅç¡AÃÒ©ú¨ä²£«~¼W¶i¸z¹D¦³¯qµß¤§®ÄªG¡A¥B³q¹L½Ã¥Í¸p¤§«O°·­¹«~»{ÃÒ¡C¡]¨ó·|²z¨Æªø / ½²­^³Ç¡^

¨Å»Äµß»P¸z¹DµßÂO¡G
¹ï©óµLµß¹}¾iªº°Êª«(gnotobiotic animal)¦Ó¨¥¡A¥u­n10­Ó¨Fªù¤ó±ìµß(Salmonella enteritidis)«K¨¬¥H¥O¨ä­P©R¡A¦ý¹ï©ó³¥¥Í¥Íªøªº°Êª«(conventional animal)«h¶·­n¤@¦Ê¸U­Ó³o¼Ëªºµß¡A¤~¯à±N¨ä±þ¦º¡Aªì¥Í°Êª«­Y¤@¶}©l«K±µÄ²¨ì³¥¥ÍÀô¹Òªº½ÆÂøµß¬Û¡A¨ä¨¾¿m¤O¬Û¹ï´£°ª¡A¦ý­Y¤@ª½¥Ñ¥ÀÅé¤p¤ß¹}¨|¡A«h¨äÅ餺·L¥Íª«¬Û¤£¨¬¡A¨¾¿m¤O¬Û§Î´î®z¡A­Y©ó¦¹®Éµ¹¤©¾A·íªº¯q¥Íµß¡A«h¥i¦^´_À³¦³ªº¨¾¿m¤O¡A¨Ì¦¹ºØºØÅã¥Ü¤F¸z¤ºµß¦s¦bªº­«­n©Ê¡C
¤HÃþ¸z¤º©Ò¤À§Gªºµß¬Û¡A¦Ü¥Ø«e©|¥¼§¹¥þ³Q¤ÀÂ÷Ų©w¥X¨Ó¡A¾Ú¦ô­p¬ù¦³400ºØ¥H¤WªºµßºØ¦s¦b¡A¨ä¤¤30~40ºØºc¦¨99%ªºµß¶q¡A¥B¹½®ñµß¸û¦n®ñµß¥eÀu¶Õ¡A¬ù¦h102~104­¿¡C¦Ó¸z¹D¤º¤£¦P°Ï°ìµß¬Û¤§¤À§G¥ç¨ü©~¦íÀô¹Ò¡B¥Í²z¤Î¿¯­¹µ¥¦]¤l¼vÅT¦Ó¦U¦³¤£¦P¡AÀHµÛ­G¤Î¸z¤ºpHªº¤£¦PÂà´«¤Î§t®ñ¶qÅܤÆ(¹½®ñµ{«×º¥¼W)¡AÅã¥Ü¥X¤£¦PÀu¶Õµß¸s¤Îµß¶qªº´À´«¡A¬ì¾Ç®a¬ã¨sÅã¥ÜÂùª[±ìµßÄÝ(Bifidobacterium sp.)¤Î¨Å»Ä¨Å±ìµßÄÝ(Lactobacillus sp.)µ¥¹ï°·±d¥¿­±¼vÅT»·¶W¹L­t­±¼vÅT¡C
¯q¥Íµßªº¸Éµ¹¹ï¸z¤ºµß¬Û³B©ó¤£Ã­©wª¬ºAªº·s¥Í¨à¤Î±µ¨ü§Ü¥Í¯À¡B¿ç®g©ÊªvÀø©Îµg¯e·P¬Vªº¯f±w¡A¸û®e©ö¦³®Ä¹F¨ì­««Ø¸z¤ºµß¬Ûªº¥Øªº¡A¦]­ì¥Í«O°·©ÊµßºØ¥i«Ü§Öªº»P«á¤Ñ¤J«Iªºµß¸sÄvª§©ÎÀ±¸É¦]ªvÀø¡B¥Í¯f¾É­Pªºµß¬Û¤£¥­Ã­²{¶H¡C¦ý´Nµß¬Û§eí©wª¬ºAªº°·±d¦¨¤H¦Ó¨¥¡A¯q¥Íµß±ý»P¤w©w´Þ¦s¦bªºµß¬ÛÄvª§¬O§xÃøªº¨Æ¡A¥i¦æªº³Ì¨Î¤èªk¤D«ùÄò­¹¥Î¯q¥Íµß¡C¡]¨ó·|²z¨Æ / ¹ù±Ò¦¨¡^


¨Å»Äµß»P¤HÅé§K¬Ì¤O¡G
¨Å»Äµßªº§K¬Ì½Õ¸`¾÷¯à·¥¨ü­«µø¡A¤@¯ë»{¬°©M¨äµßÅéªí­±¦hÁÞ¦¨¤À¦³Ãö¡A¨s³º¨Å»ÄµßµßÅé©Î¨ä¥Í²£ª«½è¦p¦ó³z¹L¤p¸z¤W¥Ö²Ó­M¦Ó¼vÅT±J¥D¤§§K¬Ì¨t²Î¡HÁöµM¨ä¾÷Âऴ¤£¤Q¤À²M·¡¡A¦ý¤w¦³¬ã¨sÅã¥Ü¨Å»Ä±ìµßµ¥²ÓµßµßÅé¯à³q¹L¸z¾À¤WªºPeyer patch°Ï°ì¦Ó¶i¤J¦å²G©Î²O¤Ú¨t²Î¡C¥t¤@¤è­±¡A¤]³\³o¨Ç¨Å»Äµß©Î¨ä¥Í²£ª«½è®Ú¥»¤£¥²Â÷¶}¸z¹D¡A§Y¥i½Õ¸`§K¬Ì¤ÏÀ³¡A³Ìªñµo²{¸z²Ó­M¦b±µÄ²¨ì¬Y¨Ç²ÓµßµßÅé®É¡A§Y·|¼W¥[¦pinterleukin 8,tumour necrosis factor ƒÑµ¥³J¥Õ½è°ò¦]¤§ªí²{¡A¦Ó³o¨Çª«½è¤wª¾¯à¬¡¤Æ¥¨¾½²Ó­M¡A¦]¦Ó¼W¶i§K¬Ì¤ÏÀ³¡C¡]¨ó·|²z¨Æªø / ½²­^³Ç¡^

¨Å»Äµßªº«O°·¥\¯à¡G
¨Å»Äµß°£¤F¼W¥[Å餺¦nµß¡B¼W±j§K¬Ì¤O¤§¥~¡AÁÙ¦³¤U¦C«O°·¥\¯à¡G
§Ü¸~½F¡G¨Å»Äµß»s¾¯©ÎÃæ»Ã¨Å³QÃÒ©ú¨ã¦³§í¨î°Êª«Åé²¾´ÓÀù©Î¤Æ¾ÇµoÀùÀù²Ó­Mª¾¼W­È¡A¤]¦³§í¨îªø´Á¹}¨|°Êª«¤§¦ÛµMµoÀù®ÄªG¡C¹ï¤HÃþ©Ò°µ½Õ¬d¬ã¨s¤]Åã¥ÜÄá­¹Ãæ»Ã¨Å¥i§í¨î¨ÅÀùµo¥Í¡A¥H¤Î»H¯ÖÀù¤§¦Aµo¡C¨ä§@¥Î¾÷Âà¸g¥Ñ°Êª«¤Î¤HÃþ¤§¹êÅç¤]³vº¥ÃÒ©ú¬O¦]¬°§K¬Ì½Õ¸`§@¥Î¤Î§í¨î¸z¤ºµßÂO²£¥Í­PÀùÃöÁpª«½è¡C
­°§C¦å²GÁx©T¾J¡G«D¬wªº°¨ÁɱڤHÄá¨ú¦h¶q¤§Ãæ»Ã¨Å¡AÁöµM¨ä¶¼­¹¤¤§t°ª¶qÁx©T¾J¡A¦ý¤ßŦ¦åºÞ¬ÛÃö¯e¯f¤ñ²v«o¬Æ§C¡CÃæ»Ã¨Å¤§­°§CÁx©T¾J§@¥Î¾÷Âà¡A¥i¯à¬O­°§C¸zºÞ§l¦¬¡C«P¶i¨xŦ±Æ¥X¡A¥H¤Î§í¨îÅ餺¦X¦¨µ¥¡C
­°¦åÀ£¡GÃæ»Ã¨Å¤¤ªº¬Y¨ÇÐ`?·|§í¨îangiotensin convereing enzyme(ACE)¦Ó¨Ï¦åÀ£­°§Cµ¥¡A¦p¥iº¸¥²«äªº­°¦åÀ£Ãæ»Ã¨Å¡A§Y§t¦³VPP¤ÎZPP¡A¥i¦³®Ä§í¨îACE¬¡©Ê¡A¦Ó¨Ï¦åÀ£­°§C¡C¡]¨ó·|²z¨Æªø / ½²­^³Ç¡^

¨Å»Äµß¦b¥«­±¤W­¹«~À³¥Î¤§²{ªp¡G
¨Å»Äµß¦b­¹«~»â°ì³Ì¤j¤§À³¥Î¬°Ãæ»Ã¨Å«~¤§»s³y¡A¥t¥~¦b¦UºØ¤õ»Lµ¥¦×»s«~¤§»s³y¡A¤]±`²K¥[¨Å»Äµß¡A¥H¥[±j«O¦s©Ê¤Î­·¨ý¡A¦UºØ¾M»s«~¡BÂæªo¡BÄÑ¥]ªº»s³y¹Lµ{¤¤¡A¨Å»Äµß¤]§êºt­«­n¨¤¦â¡C
±N¦hºØ½­ªGâBÃþ¨§Ãþ²V¦X¥H¨Å»Äµß¡B»Ã¥Àµßµ¥·L¥Íª«ªø®É¶¡µo»Ã¼ô¦¨¡A©Ò»s¦¨ªº²£«~ªñ¦~¨Ó«D±`¬y¦æ¡C§Ú°êªº¥«³õ¤W¡A¤]¦³¦hºØ¦¹Ãþ²£«~¬y³q¡A³\¦h²£«~¬Ò«a¥H¡u»Ã¯À¡v¦WºÙ¡A¨Ò¦p¤j°ª»Ã¯À¡B¹Ø»Ã¯À¡Bµ¥¡C¦¹Ãþ»s«~³Q·í§@«O°·­¹«~¡A±j½Õ¾ã¸z¡B«O¨x¡B¨¾Àù¡B±j¨­¡B¼W¶i§K¬Ìµ¥¾÷¯à¡C¡]¨ó·|²z¨Æªø / ½²­^³Ç¡^

¨Å»Äµß¥¼¨Ó²£«~ªºµo®iÁͶաG
¥Ñªñ¦~¨Ó¨Å»Äµßªº¬ã¨s¡B¬ì§Þªº¤£Â_§ó·s»Pµo®i¥H¤Î®ø¶OªÌªº»Ý¨D¨Ó¬Ý¡A¥¼¨Ó¨Å»Äµß²£«~¬ã¨sµo®iªºÁͶեiÂk¯Ç¬°¤U¦C¼ÆÂI¡G(1)¿z¿ï¨ã¯S²§©Êªº·sµß®è¡A¦p°w¹ï¤£¦P¸z­G®ø¤Æ¹D°Ï°ì»Ý­n¤£¦Pªºµß®è¡A©ÎªÌ¯S§O¹ï¬Y¨Ç¯e¯f¦³¥\®Äªºµß®è¡A¨Ò¦p»F¦]©ó«ÕªùÁ³±Û±ìµß(Helicobacter pylori) ªº­G¼ìºÅ¡B½üª¬¯f¬rµg¯e(rotavirus diarrhoea)¡B­Gª¢(gastritis)¤Î§Ü¹L±Óµ¥¯e¯f¡F(2)¥Ø«e¨Å»Äµßµß®è¦h¼Æ¨Ï¥Î©ó¨Å«~¡A¥¼¨ÓÀ¦¨à°t¤è¡B¥®¨à­¹«~¡Bµo»ÃªG¥Ä¡Bµo»Ã¨§»s«~¡B½\Ãþ­¹«~¥H¤Î¯S©wÂåÀø­¹«~µ¥¡A±N¬O²K¥[¨Å»Äµßªº·s¾÷¯à­¹«~¡C


4thProbiotics Congress: Asia